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Ketamine SLC has many mechanisms of action and the anesthetic properties for which it was developed have been shown to be very different from the antidepressant effects which derive from only partially understood pathways that are currently undergoing new and intense scrutiny. NMDA receptors account for the psychedelic and anesthetic effects while the antidepressant component is associated with other pathways, AMPA and mTOR being the two mentioned most commonly and targeted most often for future study.

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